Endocrine Abstracts

Risk factors were assessed, including lipid spectrum studies, among young patients. The survey included 225 men and 327 women. All examined patients had no clinical signs of diseases of the cardiovascular system and type 2 diabetes mellitus. The median age was 33.35 (31.15; 35.52) years. Obesity was 1.6 times more common among young men than among women (χ2 = 4.67; P = 0.03). The relative risk of developing (RR) obesity in (men/women) was 1.79 (1.23 ÷ 2.60); P</e...

Objective: To analyze correlation between the duration of diabetes mellitus (DM), renal function and androgenic state indicators in patients with DM type 1. 175 males with DM 1 type in the age of 18–55 years (39.75 ± 9.69) with the duration of disease more than 1 year were examined. The control group included 25 almost healthy males in the age 21–41 years (34.60 ± 7.80). The compensation of DM was estimated by the level of glycosylated hemoglobin (HbA1c)....

Research objective: To estimate interrelation of carbohydrate exchange compensation with indicators of blood lipids.Methods: Four hundred and seven patients suffering from diabetis of 1 and 2 types at the age of 47.20 (35.6325th–57.4275th) have been examined. The disease experience – 10.90 (6.4025th –18.4675th) years. All the examined patients have been divided into 3 groups. In the first group a...

Objectives: To analyze the indicators of carbohydrate metabolism depending on the characteristics of the manifestation of hypoglycemic reactions.Materials and methods: The study daily glucose dynamics was carried out with Medtronik MINIMED Continious Glucose Monitoring System (CGMS), USA.The standard glycose profile (4–5 per day) was measured in capillary blood with the Precision PCχTM glucose meter, MediSense. To analyz...

Objective to assess homocysteine and B12 basal levels in patients with diabetes mellitus type 1 (DM type 1) depending on anxiety level.Materials and methods: 163 patients with DM type 1 aged 18–65 years. Diabetes duration is 11.18 [4.28; 22.33] years. The level of anxiety was assessed according to the HADS scale. The homocysteine and vitamin B12 level in serum was determined. Depending on the anxiety level according to the results of the HADS score...

Introduction: Purpose of this research was the study of peculiarities of early diabetic peripheral neuropathy (DPN) manifestations in patients with diabetes mellitus depending on diabetes manifestation age, indicators of antibody level of S100B.Description of methods: Sixty-two patients with diabetes mellitus (DM) at the age of 21.4 to 75.2 (the average age was 47.7±14.1 years) including 34 males (54.8%) and 28 females (45.2%) with longevity of DM m...

The aim of the study is the search of predictors of the development of androgen deficiency in men with 1 diabetes mellitus type 1. The study included 211 men with type 1 diabetes mellitus aged 18–55 years. The median age of men was 39.00 (30.00; 45,00) years, the median duration of diabetes mellitus type 1 was 12,00 (7,00; 22,00) years. As a result of the research, it was found that an increase in the patient’s age significantly increased the risk of developing andro...

The aim of the study was to assess the effectiveness of postmenopausal osteoporosis (PMOP) therapy with denosumab.Patients and methods 32 postmenopausal women with established PMOP for a period of 24 months or more received denosumab 60 mg subcutaneously once every 6 months combined with calcium and vitamin D. A quantitative assessment of bone mineral density (BMD) was carried out before treatment, after 12 and 24 months of observation, using dual-energy X-ray absorptiometry o...

We have interviewed 246 people aged 18–55 years: 126 with DM type 2 with a duration of more than 5 years; 120 – without DM. The median body mass index (BMI) was 28.81 (23.51; 32.65) kg/m2: at DM – 29.12 (24.48; 33.35); without DM – 27.92 (22.85; 31.26). The presence of DM didn’t show any differences in eating behavior (DEBQ questionnaire) in contrast to BMI and gender. The emotiogenic style has become the leading one, the incentive for food ...

Objective: To estimate the frequency of night time hypoglycemic reaction cases in daily monitoring of the glucose in interstitial fluid under the conditions of DM 1.Materials and methods: The study of daily glucose dynamics was conducted with the use of the continuous glucose monitoring system made by the company Medtronik Minimed, USA. The study included 113 patients with DM 1. Patients ware divided into 2 groups: group 1 with hypoglycemic reaction case...